Reiner Siebert Selected Research

Androgen-Insensitivity Syndrome (Testicular Feminization)

12/2018	Epigenetic Repression of Androgen Receptor Transcription in Mutation-Negative Androgen Insensitivity Syndrome (AIS Type II).
1/2016	A Recurrent Germline Mutation in the 5'UTR of the Androgen Receptor Causes Complete Androgen Insensitivity by Activating Aberrant uORF Translation.
1/2013	Androgen receptor function links human sexual dimorphism to DNA methylation.

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Reiner Siebert Research Topics

Disease

81	Neoplasms (Cancer) 04/2024 - 03/2002
52	Lymphoma (Lymphomas) 04/2024 - 02/2002
30	B-Cell Lymphoma (Lymphoma, B Cell) 04/2024 - 10/2003
18	Hodgkin Disease (Hodgkin's Disease) 01/2023 - 05/2003
17	Genetic Translocation (Chromosomal Translocation) 12/2021 - 03/2002
14	Burkitt Lymphoma (Burkitt's Lymphoma) 12/2023 - 09/2010
13	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019 - 03/2004
12	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 04/2024 - 11/2005
12	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/2020 - 10/2003
10	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 10/2023 - 10/2003
9	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 06/2022 - 02/2003
8	Rhabdoid Tumor (Rhabdoid Tumors) 12/2021 - 02/2010
6	Carcinogenesis 10/2023 - 10/2003
6	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/2022 - 12/2007
6	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 07/2011 - 08/2003
5	Hematologic Neoplasms (Hematological Malignancy) 06/2022 - 06/2008
5	Typical Teratoid Rhabdoid Tumor 01/2022 - 06/2011
5	Chromosome Aberrations (Chromosome Abnormalities) 08/2010 - 03/2002
4	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2023 - 06/2003
4	Leukemia 11/2022 - 03/2004
4	Pathologic Complete Response 10/2022 - 12/2009
3	T-Cell Prolymphocytic Leukemia (Leukemia, T Cell, Chronic) 01/2022 - 09/2009
3	Androgen-Insensitivity Syndrome (Testicular Feminization) 12/2018 - 01/2013
3	Brain Neoplasms (Brain Tumor) 02/2013 - 10/2003
2	Squamous Cell Carcinoma of Head and Neck 03/2024 - 05/2012
2	Adenocarcinoma 10/2023 - 05/2013
2	Large Granular Lymphocytic Leukemia 01/2023 - 11/2022
2	Sarcoma (Soft Tissue Sarcoma) 01/2023 - 01/2018
2	Insulin Resistance 11/2022 - 10/2014
2	Body Weight (Weight, Body) 07/2022 - 08/2021
2	Glioma (Gliomas) 01/2022 - 10/2003
2	Non-alcoholic Fatty Liver Disease 01/2022 - 08/2013
2	Obesity 01/2022 - 10/2014
2	Disease Progression 12/2021 - 02/2011
2	Residual Neoplasm 01/2021 - 03/2006
2	Glioblastoma (Glioblastoma Multiforme) 01/2017 - 10/2003
2	Multiple Myeloma 04/2015 - 11/2007
2	Neoplasm Metastasis (Metastasis) 09/2014 - 05/2012
2	Uniparental Disomy 06/2012 - 02/2010
2	Chromosome Breakage 11/2011 - 02/2010
2	Breast Neoplasms (Breast Cancer) 01/2007 - 12/2004
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 04/2024
1	Leukocytosis (Pleocytosis) 03/2024
1	T-Cell Lymphoma (Lymphoma, T Cell) 10/2023

Drug/Important Bio-Agent (IBA)

37	Proteins (Proteins, Gene)FDA Link 01/2023 - 09/2002
20	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 05/2004
13	Transcription Factors (Transcription Factor)IBA 04/2024 - 04/2007
13	Immunoglobulins (Immunoglobulin)IBA 03/2024 - 03/2002
11	RNA (Ribonucleic Acid)IBA 04/2024 - 06/2006
10	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2007
9	Anaplastic Lymphoma KinaseIBA 10/2023 - 10/2003
9	NF-kappa B (NF-kB)IBA 10/2010 - 04/2006
8	MicroRNAs (MicroRNA)IBA 03/2024 - 03/2009
8	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 01/2020 - 06/2003
8	Cyclin D1IBA 01/2019 - 12/2005
8	hydrogen sulfite (bisulfite)IBA 03/2016 - 01/2011
7	ParaffinIBA 01/2023 - 05/2006
7	Messenger RNA (mRNA)IBA 01/2020 - 12/2004
7	CyclinsIBA 01/2019 - 12/2005
6	ChromatinIBA 01/2018 - 11/2013
5	Formaldehyde (Formol)FDA Link 11/2015 - 02/2013
4	NucleotidesIBA 11/2023 - 01/2018
4	Histones (Histone)IBA 01/2023 - 08/2006
4	Rituximab (Mabthera)FDA Link 10/2022 - 09/2009
4	IgKIBA 01/2013 - 03/2002
3	AutoantibodiesIBA 01/2023 - 01/2016
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2022 - 11/2010
3	Protein Isoforms (Isoforms)IBA 08/2022 - 09/2009
3	Insulin (Novolin)FDA Link 07/2022 - 08/2013
3	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2019 - 03/2004
3	Androgen Receptors (Androgen Receptor)IBA 12/2018 - 01/2013
2	Immunoglobulin M (IgM)IBA 03/2024 - 08/2004
2	A-Form DNA (A-DNA)IBA 01/2023 - 08/2015
2	Complement System Proteins (Complement)IBA 01/2023 - 01/2019
2	Long Noncoding RNAIBA 06/2022 - 09/2015
2	LeptinIBA 01/2022 - 08/2021
2	SMARCB1 ProteinIBA 01/2021 - 09/2014
2	AndrogensIBA 12/2018 - 07/2009
2	Phosphotransferases (Kinase)IBA 01/2016 - 03/2004
2	AnthracyclinesIBA 11/2015 - 01/2007
2	Adenosine Triphosphatases (ATPase)IBA 06/2011 - 02/2010
2	Nonsense Codon (Nonsense Mutation)IBA 06/2011 - 02/2010
2	OligonucleotidesIBA 07/2010 - 09/2008
2	Cytokine Receptors (Cytokine Receptor)IBA 07/2010 - 09/2009
2	Macrophage Colony-Stimulating FactorIBA 05/2010 - 06/2008
2	Co-Repressor ProteinsIBA 05/2010 - 06/2008
2	NF-KappaB Inhibitor alphaIBA 01/2010 - 09/2009
2	AntigensIBA 11/2007 - 08/2002
2	TNF Receptor-Associated Factor 2 (TRAF2)IBA 04/2006 - 04/2005
2	Antigen Receptors (Antigen Receptor)IBA 02/2005 - 03/2004
1	Immunoglobulin A (IgA)IBA 03/2024
1	Immunoglobulin G (IgG)IBA 03/2024
1	Keratin-19 (Keratin 19)IBA 10/2023

Therapy/Procedure

21	Therapeutics 01/2023 - 03/2006
8	Drug Therapy (Chemotherapy) 01/2023 - 01/2007
4	Ligation 10/2023 - 09/2010
2	Radiotherapy 01/2023 - 01/2020
2	Aftercare (After-Treatment) 01/2019 - 03/2004
2	Bariatric Surgery 10/2014 - 08/2013
1	Breast Implants (Breast Implant) 10/2023